Last Updated on August 26, 2025 by Casia Valdés
There’s something wonderfully nostalgic about quiche—it’s cozy, comforting, and endlessly adaptable. But when you combine it with bold Southwestern flair like roasted green chiles and smoky ham, it takes on a whole new life. This New Mexico Green Chile Bisquick Quiche is one of those dishes that feels like home, whether you’re serving it for brunch with friends or making a quick dinner on a weeknight.
It’s a recipe that doesn’t require a crust, thanks to the magic of Bisquick, which creates its own soft, bread-like base while baking. And with savory ham, melty cheese, green chiles, and just the right touch of spice, this dish delivers warmth and flavor in every bite.
Table of Contents
Why You’ll Love This Recipe
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No-fuss crustless quiche – Bisquick makes it easy and fluffy.
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Southwestern twist – The green chile brings bold, regional flavor.
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Perfect for any meal – Breakfast, brunch, lunch, or dinner.
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Freezer-friendly – Make ahead and reheat for quick meals.
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Customizable – Swap proteins or veggies with what you have.
Ingredients (Serves 6–8)
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¾ cup chopped ham
(or substitute cooked bacon or crumbled sausage) -
½ cup diced green chile
(use roasted Hatch green chile if available) -
1 cup shredded or cubed cheese
(cheddar, Monterey Jack, or a blend) -
⅓ cup chopped onion
(or substitute 1 tbsp dehydrated onion) -
2 cups milk
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½ cup Bisquick
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4 large eggs
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½ teaspoon salt
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¼ teaspoon ground black pepper
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Non-stick spray for greasing the pie plate
Optional:
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Dried parsley or paprika for color
Instructions
Step 1: Preheat the Oven
Preheat your oven to 400°F (200°C). This ensures even baking and a nicely browned top.
Step 2: Prepare the Pie Plate
Spray a 10-inch pie plate with non-stick cooking spray. This helps prevent sticking and makes cleanup easier.
Step 3: Layer the Fillings
In the bottom of the pie plate, evenly layer the chopped ham, green chile, cheese, and onions. This ensures every slice has a little of everything.
Step 4: Mix the Egg Base
In a large mixing bowl, whisk together the eggs, milk, salt, and pepper. Add the Bisquick and whisk until smooth and lump-free. The mixture should be pourable and creamy.
Step 5: Combine and Pour
Carefully pour the egg mixture over the layered ingredients in the pie plate. If you like, sprinkle a bit of dried parsley or paprika on top for color.
Step 6: Bake
Bake in the preheated oven for 35–45 minutes. Check for doneness by inserting a toothpick or knife into the center—it should come out clean. The top will be lightly golden and puffed.
Step 7: Cool and Serve
Let the quiche cool for 5–10 minutes before slicing. This allows the filling to set and makes it easier to serve.
Serving Suggestions
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Serve warm with a side salad or roasted potatoes
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Great with salsa, sour cream, or sliced avocado
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Pairs beautifully with fruit or a citrusy vinaigrette
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Add to brunch boards or breakfast buffets
Tips and Variations
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Make it vegetarian: Skip the ham and add sautéed mushrooms or spinach.
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Use different cheese: Pepper Jack, Swiss, or even feta work well.
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Meal prep ready: Store leftovers in the fridge for up to 4 days.
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Make ahead: Assemble the night before and bake fresh in the morning.
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Turn it into muffins: Use a muffin tin for individual quiche bites—great for grab-and-go meals.
Frequently Asked Questions
Can I use canned green chile?
Yes! Canned diced green chiles are great in this recipe. Drain excess liquid before adding.
What can I substitute for Bisquick?
You can make a DIY mix using ½ cup flour, 1 teaspoon baking powder, and a pinch of salt and butter.
Can I freeze this quiche?
Absolutely. Let it cool completely, then wrap and freeze slices individually. Reheat in the oven or microwave.
Why is my quiche watery?
Overbaking or not draining veggies like green chile can cause excess moisture. Use firm cheese and pat any wet ingredients dry.
Is this quiche spicy?
It has mild heat from the green chile. For more spice, use hot Hatch chile or add jalapeños.
Final Thoughts
This New Mexico Green Chile Bisquick Quiche is the definition of comfort food with a kick. The combination of soft eggs, tender ham, melted cheese, and the unmistakable flavor of green chile makes every bite feel like a trip to the Southwest. It’s simple enough for busy mornings, flavorful enough for guests, and versatile enough to make your own.
If you’re looking for a brunch centerpiece or easy weeknight dinner that delivers, this one’s for you.

New Mexico Green Chile Bisquick Quiche
Ingredients
Method
- Preheat your oven to 400°F (200°C). This ensures even baking and a nicely browned top.
- Spray a 10-inch pie plate with non-stick cooking spray. This helps prevent sticking and makes cleanup easier.
- In the bottom of the pie plate, evenly layer the chopped ham, green chile, cheese, and onions. This ensures every slice has a little of everything.
- In a large mixing bowl, whisk together the eggs, milk, salt, and pepper. Add the Bisquick and whisk until smooth and lump-free. The mixture should be pourable and creamy.
- Carefully pour the egg mixture over the layered ingredients in the pie plate. If you like, sprinkle a bit of dried parsley or paprika on top for color.
- Bake in the preheated oven for 35–45 minutes. Check for doneness by inserting a toothpick or knife into the center—it should come out clean. The top will be lightly golden and puffed.
- Let the quiche cool for 5–10 minutes before slicing. This allows the filling to set and makes it easier to serve.